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2013年3月3日,Science报道了第一例HIV儿童患者被成功治愈

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发表于 2013-3-5 08:10 | 显示全部楼层 |阅读模式

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就在昨天(3月3日in Atlanta, US),John Hopkins University的Dr. Deborah Persaud宣布第一例治愈的HIV儿童。因为搜同防止广告不能放连接,就没有提供原文的连接。感兴趣的可以搜索:

Science First Documented Case of Child Cured of HIV以下是节选的几个重要段落。中文翻译在原文之后。


The child was diagnosed with HIV at birth and immediately put on antiretroviral therapy. At 18 months, the child ceased taking antiretrovirals and was lost to follow-up. When brought back into care at 23 months, despite being off treatment for five months, the child was found to have an undetectable viral load.


该婴儿在一出生的时候被检测到HIV携带,与此同时,立刻进行抗逆转录病毒药物治疗。18个月后,该婴儿停止治疗并失去后续跟踪记录。23个月是,该婴儿体内几乎检测不到HIV病毒,尽管此时已经停止治疗近5个月。


According to Dr. Persaud, comprehensive tests have confirmed beyond doubt that both mother and child were HIV positive when the child was born, and today no signs of HIV infection in the child can be detected by the most sensitive means available.


根据Persaud博士的描述,在婴儿出生的时候,系统的HIV检测结果显示该婴儿和其母亲均呈HIV阳性,但是现在,即使最精确的检测方法也检测不到婴儿体内的HIV病毒。


"Given that this cure appears to have been achieved by antiretroviral therapy alone," said Dr. Johnston, "it is also imperative that we learn more about a newborn's immune system, how it differs from an adult's, and what factors made it possible for the child to be cured."


“鉴于首次治愈案例是仅仅通过抗逆转录病毒药物治疗实现的,Johnston博士说道:“我们迫切的想知道更多关于出生婴儿的免疫系统,它跟成人的免疫系统有何不同,是什么因素使治愈HIV成为可能的。”


"We are proud to have played a leading role in bringing this first pediatric HIV cure to light," said amfAR CEO Kevin Robert Frost. "The case is a startling reminder that a cure for HIV could come in ways we never anticipated, and we hope this is the first of many children cured of HIV in the months and years to come."



“我们非常自豪在这次宣布的儿童HIV治愈的案例中起到重要作用,”amfAR的首席执行官说道:“这个案例预示着治疗HIV这一课题的攻克可能以我们从未想过的方式实现,我们也希望在未来的几年中,有更多的HIV儿童携带者能够被通过这种方法治愈。”

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